Journal Detail

Research Article

ArticleID :NJQLN/2024/10/04/01

Fractal Analysis of Mining Wastewater Time Series Parameters: Balkhash Urban Region and Sayak Ore District

Issue No. 04 (Oct-Dec)

Authors: Andrii Biloshchytskyi, Oleksandr Kuchanskyi, Alexandr Neftissov, Yurii Andrashko, Svitlana Biloshchytska and Ilyas Kazambayev

The population life and health quality are significantly reduced due to water resources pollution caused by heavy metals, especially in urban agglomerations located close to metal ore mining and processing facilities. The greatest environmental pollution occurs during the extraction of Cu, Zn, and Pb. In this study, a fractal R/S analysis of wastewater discharge indicators time series from a metal ore mining facility located in the Sayak ore district in the Republic of Kazakhstan (turbidity, electrical conductivity, flow magnitude, and pH level) was carried out. A sharp increase in the flow rate was recorded from 10 to 15 July 2024 and an increase in the electrical conductivity from 4 to 26 July 2024. However, the latest type of indicator assessment does not exceed the critical level for life. The presence of electrical conductivity indicators time series long-term memory and persistence was also recorded (the Hurst exponent for the electrical conductivity time series is fixed in the 0.56 to 0.59 range and does not go below the threshold value for randomness according to the Anis-Lloyd formula). Thus, the value-changing process is controlled and stable, and minor changes in turbidity indicate that these releases do not significantly harm the environment. Despite this, the results obtained do not allow for a comprehensive analysis of the state of releases as the data from all deposits is not available. Therefore, due to the time constraints of the data provided for analysis, it is difficult to fully assess the impact of specific metal ore mining facilities on the environmental safety of the Balkhash urban region. In addition, many studies indicate very high risks of chronic diseases for the population living in this region. The findings of this study enable us to conclude that the application of fractal analysis and the calculation of fractal characteristics for time series of emissions can serve as an indicator of the environmental status within the given area. This information can be used by environmental services to build reliable environmental pollution monitoring systems.

Keywords: mining wastewater; R/S analysis; Balkhash urban region; Hurst exponent; Sayak ore district; time series analysis

How To Cite this Article

© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).

Research Article

ArticleID :NJQLN/2024/10/04/02

Identifying the Relationship Between Residential Type and Health Outcomes of the Community-Dwelling Thai Older Adults in the Baseline Analysis of a Cluster-Randomized Controlled Trial

Issue No. 04 (Oct-Dec)

Authors: Nadila Mulati, Myo Nyein Aung, Saiyud Moolphate, Thin Nyein Nyein Aung, Yuka Koyanagi, Siripen Supakankunti and Motoyuki Yuasa

Background/Objectives: As people age, their environment plays a critical role in shaping their health. With Thailand’s rapidly aging population, it is crucial to understand how different living environments affect the well-being of older adults. This study examines differences in biopsychosocial health indicators between older adults living in village communities and private housing estates in Chiang Mai, Thailand. Methods: A cross-sectional study was conducted using baseline data from the Community-Integrated Intermediary Care (CIIC) Service Model, a Cluster Randomized Controlled Trial in Thailand (TCTR20190412004). The study included 2788 older adults (aged 60+). Of these, 89.49% resided in village communities, and 10.51% in private housing estates. Validated instruments were used to assess health indicators. Descriptive statistics, multivariate analysis of variance, and multiple logistic regression analyses were performed. Results: Older adults in private housing estates had significantly lower odds of experiencing pain or discomfort (Adj OR: 0.64, 95% CI: 0.49–0.84) and were 1.36 times more likely to report positive perceived health. However, they had lower odds of perceiving themselves as physically and socially active (Adj OR: 0.74, 95% CI: 0.57–0.97) and were 0.30 times less likely to rate their quality of life higher (Adj OR: 0.30, 95% CI: 0.22–0.40) compared to their village community counterparts. Conclusions: The residential environment significantly influences older adults’ health and well-being. Tailored health promotion interventions should leverage the unique strengths of both village communities and private housing estates to enhance social connections, physical activity, and quality of life, promoting healthy, active aging across diverse settings. Keywords: healthy aging; active aging; built environment; gated communities; residential type; health promotion

How To Cite this Article

© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).

Review Article

ArticleID :NJQLN/2024/10/04/03

Primary Prevention Strategy for Non-Communicable Diseases (NCDs) and Their Risk Factors: The Role of Intestinal Microbiota

Issue No. 04 (Oct-Dec)

Authors: Itzel Ivonn López-Tenorio, Óscar Rodrigo Aguilar-Villegas, Yoshua Espinoza-Palacios, Lorena Segura-Real, Berenice Peña-Aparicio, Amedeo Amedei and María Magdalena Aguirre-García

Non-communicable diseases (NCDs) are the leading cause of morbidity and mortality worldwide. These conditions have numerous health consequences and significantly impact patients’ lifestyles. Effective long-term treatment is essential since NCDs are irreversible. Therefore, primary healthcare must be both exclusive and of the highest quality, ensuring comprehensive care. The primary goal should be to improve quality of life with a focus on patients, families, and communities, as most of these diseases can be prevented and controlled, although not cured. Several factors have been linked to individual health, including social, cultural, and economic aspects, lifestyle, and certain environmental factors, including work, that can have positive or negative effects. More of these variables may contribute to the onset of NCDs, which are defined by their chronic nature, propensity for prolongation, and generally slow rate of progression. Examples of NCDs include hypertension, type 2 diabetes (T2D), dyslipidemia, and fatty liver disease linked to metabolic dysfunction. The onset of these diseases has been associated with an imbalance in certain microbial niches, such as the gut, which hosts billions of microorganisms performing multiple metabolic functions, such as the production of metabolites like bile acids (BAs), short-chain fatty acids (SCFAs), and trimethylamine N-oxide (TMAO). Therefore, lifestyle changes and personal habits can significantly impact the gut microbiota (GM), potentially preventing chronic diseases associated with metabolism. NCDs are highly prevalent worldwide, prompting increased attention to strategies for modifying the intestinal microbiota (IM). Approaches such as probiotics, prebiotics, synbiotics, and fecal transplantation (FMT) have demonstrated improvements in the quality of life for individuals with these conditions. Additionally, lifestyle changes and the adoption of healthy habits can significantly impact IM and may help prevent chronic diseases related to metabolism. Therefore, the main aim of this review is to analyze and understand the importance of microbiota intervention in the prevention of noncommunicable diseases. R3:A1

Keywords: intestinal microbiota; non-communicable diseases; hypertension; type 2 diabetes; obesity; dyslipidemia

How To Cite this Article

© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/)

Review Article

ArticleID :NJQLN/2024/10/04/04

Probiotic, Postbiotic, and Paraprobiotic Effects of Lactobacillus rhamnosus as a Modulator of Obesity-Associated Factors

Issue No. 04 (Oct-Dec)

Authors: Gabriela López-Almada, María Esther Mejía-León and Norma Julieta Salazar-López

Obesity is a pandemic currently affecting the world’s population that decreases the quality of life and promotes the development of chronic non-communicable diseases. Lactobacillus rhamnosus is recognized for multiple positive effects on obesity and overall health. In fact, such effects may occur even when the microorganisms do not remain alive (paraprobiotic effects). This raises the need to elucidate the mechanisms by which obesity-associated factors can be modulated. This narrative review explores recent findings on the effects of L. rhamnosus, particularly, its postbiotic and paraprobiotic effects, on the modulation of adiposity, weight gain, oxidative stress, inflammation, adipokines, satiety, and maintenance of intestinal integrity, with the aim of providing a better understanding of its mechanisms of action in order to contribute to streamlining its clinical and therapeutic applications. The literature shows that L. rhamnosus can modulate obesity-associated factors when analyzed in vitro and in vivo. Moreover, its postbiotic and paraprobiotic effects may be comparable to the more studied probiotic actions. Some mechanisms involve regulation of gene expression, intracellular signaling, and enteroendocrine communication, among others. We conclude that the evidence is promising, although there are still multiple knowledge gaps that require further study in order to fully utilize L. rhamnosus to improve human health.

Keywords: supernatants; Lactobacillus rhamnosus GG supernatant; oxidative stress; adiposity; inflammation; adipokines

How To Cite this Article

© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).